MRI & Open MRIJune 21, 20265 min read

NeuroQuant Brain MRI: How AI Volumetric Analysis Detects Early Brain Changes

NeuroQuant is FDA-cleared AI that measures the volume of 68 brain regions and compares them to age-matched norms — helping detect early changes a standard MRI read may miss.

Medically reviewed by Milind Patel, MD, Medical Director - CAQ Neuroradiologist

A standard brain MRI gives your radiologist a detailed picture — but the human eye can only estimate whether a brain structure is subtly smaller than it should be. NeuroQuant changes that. It is FDA-cleared artificial-intelligence software that measures the actual volume of dozens of brain regions and compares them, region by region, to a large database of healthy people the same age and sex as you.

For patients worried about memory, monitoring multiple sclerosis, or recovering from a head injury, that quantitative precision can reveal meaningful change earlier than a visual read alone.

What Is NeuroQuant?

NeuroQuant is automated brain-volumetry software developed by Cortechs.ai. It takes the images from an ordinary 3D MRI of your brain and, in a matter of minutes, segments the brain into structures and calculates the volume of each one. Those volumes are then plotted against age- and sex-matched reference norms so your physician can see exactly where you fall — typically expressed as a percentile.

It is the same category of technology used at leading academic medical centers, now available locally in Pinellas County.

How It Works

  1. Standard 3D MRI. You have a normal brain MRI on our 3T or 1.5T scanner — no extra time on the table, no contrast required for the volumetric protocol.
  2. AI segmentation. The CorTechs platform automatically identifies and measures brain structures across as many as 68 regions.
  3. Comparison to norms. Each measured volume is compared to a normative database matched to your age and sex.
  4. Radiologist read. A board-certified radiologist interprets both your images and the NeuroQuant report together — the AI assists the physician; it does not replace the physician.

What It Measures

NeuroQuant quantifies structures that matter most in neurological care, including:

  • Hippocampus — a key memory center; volume loss here can be an early signal in some dementias
  • Ventricles — fluid-filled spaces that can enlarge as surrounding tissue is lost
  • White matter — including white-matter lesion volume relevant to MS monitoring
  • Cortical thickness and lobar volumes — frontal, temporal, parietal, and occipital regions

Because the measurements are numeric, they can be repeated over time to track whether a structure is stable, shrinking, or responding to treatment.

Who Should Consider It

NeuroQuant may be appropriate if you have:

  • Memory or cognitive concerns — new forgetfulness, word-finding trouble, or a family member's worry
  • A family history of dementia or Alzheimer's disease and want a quantitative baseline
  • Traumatic brain injury (TBI) follow-up, where volume loss can be subtle
  • Multiple sclerosis, where serial brain- and lesion-volume tracking guides management

It is not a diagnosis on its own. NeuroQuant is a tool that helps your physician interpret your brain MRI with greater objectivity — always discuss results in the context of your full clinical picture.

What the Report Looks Like

Instead of a paragraph of impressions alone, you and your physician receive a structured, color-coded report. Each brain region is shown with its measured volume and a percentile chart against the normal range — green where a structure sits comfortably within normal limits, and flagged where a volume falls below (or above) the expected range for your age. That makes it easy to see at a glance which structures, if any, deserve attention or follow-up.

How AMI Does It

At AMI, NeuroQuant runs on qualifying brain MRI studies performed on our 3T MRI (for the sharpest volumetric data) or our 1.5T MRI. The NeuroQuant analysis is generated automatically and delivered alongside the interpretation of a board-certified radiologist — often the same day as your scan. Your referring physician receives both the images and the quantitative report.

Self-Pay — No Referral Needed

Self-pay patients do not need a referral. Our medical director reviews each request, and most self-pay patients are accommodated quickly. Because pricing depends on the specific protocol, please call (727) 398-5999 for self-pay pricing.

Schedule Your NeuroQuant Brain MRI

Learn more about NeuroQuant Brain MRI, then schedule online or call (727) 398-5999. If you are weighing broader preventive imaging, you may also want to read about our whole-body MRI.

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